The performance of a depth-of-interaction preclinical small animal PET scanner (GEeXploreVista) has been investigated. To this purpose several parameters such as spatial resolution, sensitivity, scatter fraction and noise equivalent counts were measured. Because of the different mean positron range of F-18 and C-11 attention was focused on measuring the effect of such difference on the scanner spatial resolution. The spatial resolution was measured using a point, a line source and a high resolution phantom. Scatter fraction and noise equivalent counts were measured using mouse and rat size objects. Results show that the eXploreVista provides a spatial resolution of 1.48 mm and sensitivity up to6%. In vivo images of small mice were also presented.
A.E.Spinelli, D.D'Ambrosio, C.Pettinato, S.Trespidi, C.Nanni, V.Ambrosini, et al. (2007). Performance evaluation of a small animal PET scanner. Spatial resolution characterization using F-18 and C-11. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT, A571, 215-218 [10.1016/j.nima.2006.10.066].
Performance evaluation of a small animal PET scanner. Spatial resolution characterization using F-18 and C-11.
AMBROSINI, VALENTINA;BALDAZZI, GIUSEPPE;
2007
Abstract
The performance of a depth-of-interaction preclinical small animal PET scanner (GEeXploreVista) has been investigated. To this purpose several parameters such as spatial resolution, sensitivity, scatter fraction and noise equivalent counts were measured. Because of the different mean positron range of F-18 and C-11 attention was focused on measuring the effect of such difference on the scanner spatial resolution. The spatial resolution was measured using a point, a line source and a high resolution phantom. Scatter fraction and noise equivalent counts were measured using mouse and rat size objects. Results show that the eXploreVista provides a spatial resolution of 1.48 mm and sensitivity up to6%. In vivo images of small mice were also presented.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
