New pharmacological treatments of acutely decompensated heart failure. Critical review of new drugs options.

Acutely decompensated heart failure (ADHF) represents the leading reason for hospital admissions in patients over 65 years of age. Aim of this paper is to analyze new approaches for acute heart failure treatment. Effective new treatments should be found to reduce the length of hospital stay and its correlate costs in CHF symptomatic and asymptomatic patients. According to the Authors' personal experience and new clinical data from controlled clinical trials, it is mandatory to substitute traditional inotropes, in acutely decompensated heart failure, as first option, with the advice to use alternative drugs, at least in patients with the cardio renal syndrome. The Author consider the possibility of treatment of ADHF trying toblock mainly compensatory systems and neurohermons.