Gastrointestinal stromal tumors (GIST) are uncommon mesenchymal tumors of the gastrointestinal (GI) tract, accounting for 0.1% to 3% of all GI malignancies. Paediatric GIST have an annual incidence of 0.02 per million children, have a female predisposition, are usually located in the stomach (50–60%) and in up to 85% of cases CD117-cKit or PDGFRA mutation is absent, resulting in a decreased efficacy of the target therapy.
Mario Lima, Tommaso Gargano, Giovanni Ruggeri, Andrea Pession, Arianna Mariotto, Michela Maffi (2015). "Laparoscopic resection of a rare gastrointestinal stromal tumor in children". SPRINGERPLUS, 4, 1-7 [10.1186/s40064-015-0850-9].
"Laparoscopic resection of a rare gastrointestinal stromal tumor in children"
LIMA, MARIO;GARGANO, TOMMASO;RUGGERI, GIOVANNI;
2015
Abstract
Gastrointestinal stromal tumors (GIST) are uncommon mesenchymal tumors of the gastrointestinal (GI) tract, accounting for 0.1% to 3% of all GI malignancies. Paediatric GIST have an annual incidence of 0.02 per million children, have a female predisposition, are usually located in the stomach (50–60%) and in up to 85% of cases CD117-cKit or PDGFRA mutation is absent, resulting in a decreased efficacy of the target therapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
