The present paper describes the production, using a microfluidic approach, of microparticles (constituted of cellulose acetate) and O/ W emulsions (constituted of PEG-6 corn oil droplets). The general production strategy is based on the formation of water-in-oil multiphase flow by a focusing mechanism (X-junction chip). The innovative aspect of the work is represented by the fabrication procedure for the microfluidic chip production. The chips were designed and fabricated by a low cost approach using a shrinkable biocompatible polymer.
L. CAPRETTO, S. FOCAROLI, X.L. ZHANG, S. MAZZITELLI, C. NASTRUZZI (2010). PRODUCTION OF LOW COST MICROFLUIDIC CHIPS BY A “SHRINKING” APPROACH: APPLICATIONS TO EMULSION AND MICROPARTICLE PRODUCTION. JOURNAL OF CONTROLLED RELEASE, 148, e26-e28 [10.1016/j.jconrel.2010.07.038].
PRODUCTION OF LOW COST MICROFLUIDIC CHIPS BY A “SHRINKING” APPROACH: APPLICATIONS TO EMULSION AND MICROPARTICLE PRODUCTION
FOCAROLI, STEFANO;
2010
Abstract
The present paper describes the production, using a microfluidic approach, of microparticles (constituted of cellulose acetate) and O/ W emulsions (constituted of PEG-6 corn oil droplets). The general production strategy is based on the formation of water-in-oil multiphase flow by a focusing mechanism (X-junction chip). The innovative aspect of the work is represented by the fabrication procedure for the microfluidic chip production. The chips were designed and fabricated by a low cost approach using a shrinkable biocompatible polymer.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
