Different substituted ferrocene–guanine conjugates were prepared, and their electrochemical behavior was investigated. A new approach for the introduction of ferrocene in guanine’s 9-position through a quite effective SN1-type reaction was disclosed. The electrochemical behavior of the various derivatives can be used as standard for the quantification and analysis of DNA strands.
New Approaches toward Ferrocene–Guanine Conjugates: Synthesis and Electrochemical Behavior
IURLO, MATTEO;MENGOZZI, LUCA;RAPINO, STEFANIA;MARCACCIO, MASSIMO;PERONE, ROSARIA CARMELA;MASIERO, STEFANO;COZZI, PIER GIORGIO;PAOLUCCI, FRANCESCO
2014
Abstract
Different substituted ferrocene–guanine conjugates were prepared, and their electrochemical behavior was investigated. A new approach for the introduction of ferrocene in guanine’s 9-position through a quite effective SN1-type reaction was disclosed. The electrochemical behavior of the various derivatives can be used as standard for the quantification and analysis of DNA strands.File in questo prodotto:
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