In the presence of a thiourea catalyst, b-CF3 nitroalkenes react with Hantzsch esters in a highly enantioselective fashion, giving a broad range of b-CF3 amine precursors with a tertiary stereocentre at the b-position. This reaction represents the first general catalytic enantioselective approach to this important class of b-CF3 amines.

Catalytic highly enantioselective transfer hydrogenation of β-trifluoromethyl nitroalkenes. An easy and general entry to optically active β-trifluoromethyl amines / Emilie Martinelli;Anna Chiara Vicini;Michele Mancinelli;Andrea Mazzanti;Paolo Zani;Luca Bernardi;Mariafrancesca Fochi. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - STAMPA. - 51:(2015), pp. 658-660. [10.1039/C4CC07801B]

Catalytic highly enantioselective transfer hydrogenation of β-trifluoromethyl nitroalkenes. An easy and general entry to optically active β-trifluoromethyl amines

MANCINELLI, MICHELE;MAZZANTI, ANDREA;ZANI, PAOLO;BERNARDI, LUCA;FOCHI, MARIAFRANCESCA
2015

Abstract

In the presence of a thiourea catalyst, b-CF3 nitroalkenes react with Hantzsch esters in a highly enantioselective fashion, giving a broad range of b-CF3 amine precursors with a tertiary stereocentre at the b-position. This reaction represents the first general catalytic enantioselective approach to this important class of b-CF3 amines.
2015
Catalytic highly enantioselective transfer hydrogenation of β-trifluoromethyl nitroalkenes. An easy and general entry to optically active β-trifluoromethyl amines / Emilie Martinelli;Anna Chiara Vicini;Michele Mancinelli;Andrea Mazzanti;Paolo Zani;Luca Bernardi;Mariafrancesca Fochi. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - STAMPA. - 51:(2015), pp. 658-660. [10.1039/C4CC07801B]
Emilie Martinelli;Anna Chiara Vicini;Michele Mancinelli;Andrea Mazzanti;Paolo Zani;Luca Bernardi;Mariafrancesca Fochi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/396755
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