Two novel neutral complexes based on platinum metal ions, a tridentate ligand, and a pyridine bearing a beta-lactam unit have been synthesized and their photophysical properties investigated. The complexes show interesting emission properties that, in the solid state, are dominated by the formation of aggregates due to the square-planar geometry of the Pt-II species. Importantly, the formation of closed-shell metal center dot center dot center dot metal interactions in such aggregates leads to new excited states that conveniently allow excitation in the visible region. The combination of the biologically active azetidinone agent and the intense and long-lived emission are of particular interest for developing efficient multifunctional biomedical systems

beta-Lactam Bioconjugates Bearing Luminescent Platinum(II) Tags: Synthesis and Photophysical Characterization

GIACOMINI, DARIA
2014

Abstract

Two novel neutral complexes based on platinum metal ions, a tridentate ligand, and a pyridine bearing a beta-lactam unit have been synthesized and their photophysical properties investigated. The complexes show interesting emission properties that, in the solid state, are dominated by the formation of aggregates due to the square-planar geometry of the Pt-II species. Importantly, the formation of closed-shell metal center dot center dot center dot metal interactions in such aggregates leads to new excited states that conveniently allow excitation in the visible region. The combination of the biologically active azetidinone agent and the intense and long-lived emission are of particular interest for developing efficient multifunctional biomedical systems
Roberto Soldati; Alessandro Aliprandi; Matteo Mauro; Luisa De Cola; Daria Giacomini
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/396731
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
social impact