Preliminary studies of the elementary steps involved in the reaction of a chiral methyl carbonyl bioxazoline Pd(II) complex with aromatic olefins and CO have allowed development of a new enantioselective catalytic carbonylation process, leading to g-ketoester derivatives with high yield and good enantiomeric excess. The intermediate palladacycle complexes have been isolated and characterized by NMR spectroscopy and X-ray diffraction. Factors that govern the stereoselectivity of the olefin carbonylation process are discussed.
C. CARFAGNA, G. GATTI, L. MOSCA, P. NATANTI, P. PAOLI, P. ROSSI, et al. (2011). Carbonylation of styrenes catalyzed by bioxazoline Pd(II) complexes: mechanism of enantioselectivity. DALTON TRANSACTIONS, 40, 6792-6801 [10.1039/C1DT10101C].
Carbonylation of styrenes catalyzed by bioxazoline Pd(II) complexes: mechanism of enantioselectivity
CARFAGNA, CARLA;
2011
Abstract
Preliminary studies of the elementary steps involved in the reaction of a chiral methyl carbonyl bioxazoline Pd(II) complex with aromatic olefins and CO have allowed development of a new enantioselective catalytic carbonylation process, leading to g-ketoester derivatives with high yield and good enantiomeric excess. The intermediate palladacycle complexes have been isolated and characterized by NMR spectroscopy and X-ray diffraction. Factors that govern the stereoselectivity of the olefin carbonylation process are discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
