Preliminary studies of the elementary steps involved in the reaction of a chiral methyl carbonyl bioxazoline Pd(II) complex with aromatic olefins and CO have allowed development of a new enantioselective catalytic carbonylation process, leading to g-ketoester derivatives with high yield and good enantiomeric excess. The intermediate palladacycle complexes have been isolated and characterized by NMR spectroscopy and X-ray diffraction. Factors that govern the stereoselectivity of the olefin carbonylation process are discussed.
Carbonylation of styrenes catalyzed by bioxazoline Pd(II) complexes: mechanism of enantioselectivity / C. CARFAGNA; G. GATTI; L. MOSCA; P. NATANTI; P. PAOLI; P. ROSSI; B. GABRIELE; G. SALERNO. - In: DALTON TRANSACTIONS. - ISSN 1477-9226. - STAMPA. - 40:(2011), pp. 6792-6801. [10.1039/C1DT10101C]
Carbonylation of styrenes catalyzed by bioxazoline Pd(II) complexes: mechanism of enantioselectivity
CARFAGNA, CARLA;
2011
Abstract
Preliminary studies of the elementary steps involved in the reaction of a chiral methyl carbonyl bioxazoline Pd(II) complex with aromatic olefins and CO have allowed development of a new enantioselective catalytic carbonylation process, leading to g-ketoester derivatives with high yield and good enantiomeric excess. The intermediate palladacycle complexes have been isolated and characterized by NMR spectroscopy and X-ray diffraction. Factors that govern the stereoselectivity of the olefin carbonylation process are discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
