he development and persistence of anti-West Nile Virus (WNV) immunoglobulin G (IgG)- and IgM-specific antibodies were investigated in 68 asymptomatic blood donors (BDs) previously tested as positive between October, 2008, and September, 2009, and living in northeastern Italy. Our study showed that WNV-specific IgG titers became negative (41%) or decreased (33%) in a large percentage of BDs, while they increased in a smaller percentage (10%); 16% of BDs showed no titer variation. Reversion to seronegative status within a short time frame suggests that WNV surveillance should be maintained year after year.
Persistence of anti-west nile virus-specific antibodies among asymptomatic blood donors in Northeastern Italy / Pierro A;Gaibani P;Manisera C;Rossini G;Finarelli AC;Ghinelli F;Macini P;Landini MP;Sambri V. - In: VECTOR BORNE AND ZOONOTIC DISEASES. - ISSN 1530-3667. - STAMPA. - 13:12(2013), pp. 892-893. [10.1089/vbz.2012.1157]
Persistence of anti-west nile virus-specific antibodies among asymptomatic blood donors in Northeastern Italy.
GAIBANI, PAOLO;ROSSINI, GIADA;MACINI, PIERLUIGI;LANDINI, MARIA PAOLA;SAMBRI, VITTORIO
2013
Abstract
he development and persistence of anti-West Nile Virus (WNV) immunoglobulin G (IgG)- and IgM-specific antibodies were investigated in 68 asymptomatic blood donors (BDs) previously tested as positive between October, 2008, and September, 2009, and living in northeastern Italy. Our study showed that WNV-specific IgG titers became negative (41%) or decreased (33%) in a large percentage of BDs, while they increased in a smaller percentage (10%); 16% of BDs showed no titer variation. Reversion to seronegative status within a short time frame suggests that WNV surveillance should be maintained year after year.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
