he development and persistence of anti-West Nile Virus (WNV) immunoglobulin G (IgG)- and IgM-specific antibodies were investigated in 68 asymptomatic blood donors (BDs) previously tested as positive between October, 2008, and September, 2009, and living in northeastern Italy. Our study showed that WNV-specific IgG titers became negative (41%) or decreased (33%) in a large percentage of BDs, while they increased in a smaller percentage (10%); 16% of BDs showed no titer variation. Reversion to seronegative status within a short time frame suggests that WNV surveillance should be maintained year after year.
Pierro A, Gaibani P, Manisera C, Rossini G, Finarelli AC, Ghinelli F, et al. (2013). Persistence of anti-west nile virus-specific antibodies among asymptomatic blood donors in Northeastern Italy. VECTOR BORNE AND ZOONOTIC DISEASES, 13(12), 892-893 [10.1089/vbz.2012.1157].
Persistence of anti-west nile virus-specific antibodies among asymptomatic blood donors in Northeastern Italy.
GAIBANI, PAOLO;ROSSINI, GIADA;MACINI, PIERLUIGI;LANDINI, MARIA PAOLA;SAMBRI, VITTORIO
2013
Abstract
he development and persistence of anti-West Nile Virus (WNV) immunoglobulin G (IgG)- and IgM-specific antibodies were investigated in 68 asymptomatic blood donors (BDs) previously tested as positive between October, 2008, and September, 2009, and living in northeastern Italy. Our study showed that WNV-specific IgG titers became negative (41%) or decreased (33%) in a large percentage of BDs, while they increased in a smaller percentage (10%); 16% of BDs showed no titer variation. Reversion to seronegative status within a short time frame suggests that WNV surveillance should be maintained year after year.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
