The production of disease-specific lines of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) opened new opportunities to study genetic cardiac disorders such as Long QT (LQT) syndrome. We focused on the computational modelling of hiPSC-CMs with LQT1 syndrome which reduces the slow delayed rectifying, IKs, current. © 2013 CCAL.
Computational modelling of LQT1 in human induced pluripotent stem cell derived cardiomyocytes / M. b. Paci;J. b. Hyttinen;S. Severi. - In: COMPUTING IN CARDIOLOGY. - ISSN 2325-8861. - ELETTRONICO. - 40:(2013), pp. 1239-1242.
Computational modelling of LQT1 in human induced pluripotent stem cell derived cardiomyocytes
SEVERI, STEFANO
2013
Abstract
The production of disease-specific lines of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) opened new opportunities to study genetic cardiac disorders such as Long QT (LQT) syndrome. We focused on the computational modelling of hiPSC-CMs with LQT1 syndrome which reduces the slow delayed rectifying, IKs, current. © 2013 CCAL.File in questo prodotto:
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