The production of disease-specific lines of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) opened new opportunities to study genetic cardiac disorders such as Long QT (LQT) syndrome. We focused on the computational modelling of hiPSC-CMs with LQT1 syndrome which reduces the slow delayed rectifying, IKs, current. © 2013 CCAL.
M. b. Paci, J. b. Hyttinen, S. Severi (2013). Computational modelling of LQT1 in human induced pluripotent stem cell derived cardiomyocytes. COMPUTING IN CARDIOLOGY, 40, 1239-1242.
Computational modelling of LQT1 in human induced pluripotent stem cell derived cardiomyocytes
SEVERI, STEFANO
2013
Abstract
The production of disease-specific lines of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) opened new opportunities to study genetic cardiac disorders such as Long QT (LQT) syndrome. We focused on the computational modelling of hiPSC-CMs with LQT1 syndrome which reduces the slow delayed rectifying, IKs, current. © 2013 CCAL.File in questo prodotto:
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