Three sets of oligomers containing the 4-carboxy-5-methyl-oxazolidin-2-one (Oxd) moiety have been synthesized with the aim of checking whether these molecules are able to fold in ordered structures: A set [Boc-(L-Ala-L-Oxd)n-OR], B set [Boc-(L-Ala-D-Oxd)n-OR] and C set [Boc-(Aib-L-Oxd)n-OR] preferential conformations have been analyzed with IR absorption, NMR and CD. We have noticed that in these oligomers three stabilizing effects are active: (i) the rigid Oxd –CO-N(CH

Oxazolidin-2-ones-Containing Pseudopeptides that Fold into beta-Bend Ribbon Spirals

TOMASINI, CLAUDIA;LUPPI, GIANLUIGI;MONARI, MAGDA
2006

Abstract

Three sets of oligomers containing the 4-carboxy-5-methyl-oxazolidin-2-one (Oxd) moiety have been synthesized with the aim of checking whether these molecules are able to fold in ordered structures: A set [Boc-(L-Ala-L-Oxd)n-OR], B set [Boc-(L-Ala-D-Oxd)n-OR] and C set [Boc-(Aib-L-Oxd)n-OR] preferential conformations have been analyzed with IR absorption, NMR and CD. We have noticed that in these oligomers three stabilizing effects are active: (i) the rigid Oxd –CO-N(CH
2006
C. Tomasini; G. Luppi; M. Monari
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/37297
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 55
  • ???jsp.display-item.citation.isi??? 52
social impact