We present a further step in developing an in silico model that simulates the immune system responses to tumor cells in vaccinated mice. Our study is based on our previous model that simulates the cancer - immune System competition activated by a tumor vaccine. In what follows, we show first results on effects of deconstructing the components of Triplex vaccine that are in very good agreement with in vivo results.
F. Pappalardo, P.-L. Lollini, S. Motta, E. Mastriani. (2006). Model deconstruction of an immunoprevention vaccine. Berlin, Heidelberg : Springer.
Model deconstruction of an immunoprevention vaccine
LOLLINI, PIER LUIGI;
2006
Abstract
We present a further step in developing an in silico model that simulates the immune system responses to tumor cells in vaccinated mice. Our study is based on our previous model that simulates the cancer - immune System competition activated by a tumor vaccine. In what follows, we show first results on effects of deconstructing the components of Triplex vaccine that are in very good agreement with in vivo results.File in questo prodotto:
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