Thrombophilia is the term now used to describe predisposition to increased risk of venous and occasionally arterial thromboembolism due to hematological abnormalities. It can be a multifactorial disorder where congenital defects of anticoagulant or procoagulant factors may be combined with acquired hematological abnormalities. It should be considered in patients with a documented unexplained thrombotic episode or a positive family history. The aim of this document is to provide guidelines for investigation and management of patients with thrombophilia in the presence or absence of venous thromboembolism (VTE).
Thrombophilia and venous thromboembolism. International consensus statement. Guidelines according to scientific evidence / The European Genetics Foundation; The Cardiovascular Disease Educational and Research Trust; The International Union of Angiology; The Mediterranean League on Thromboembolism; Nicolaides AN.; Breddin HK.; Carpenter P.; Coccheri S.; Conard J.; De Stefano V.; Elkoofy N.; Gerotziafas G.; Guermazi S.; Haas S.; Hull R.; Kalodiki E.; Kristof V.; Michiels JJ.; Myers K.; Pineo G.; Prandoni P.; Romeo G.; Samama MM.; Simonian S.; Xenophonthos S.. - In: INTERNATIONAL ANGIOLOGY. - ISSN 0392-9590. - ELETTRONICO. - 24:(2005), pp. 1-26.
Thrombophilia and venous thromboembolism. International consensus statement. Guidelines according to scientific evidence.
COCCHERI, SERGIO;ROMEO, GIOVANNI;
2005
Abstract
Thrombophilia is the term now used to describe predisposition to increased risk of venous and occasionally arterial thromboembolism due to hematological abnormalities. It can be a multifactorial disorder where congenital defects of anticoagulant or procoagulant factors may be combined with acquired hematological abnormalities. It should be considered in patients with a documented unexplained thrombotic episode or a positive family history. The aim of this document is to provide guidelines for investigation and management of patients with thrombophilia in the presence or absence of venous thromboembolism (VTE).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
