Although the 2004 World Health Organization classification attempted to clarify the role of combined neuroendocrine tumors of the lung, these are yet to be clearly defined. Prob- lems concerning clinical behavior are a result of unclear pathophysiology, the limited number of published cases, and the heterogeneity of histotypes involved. The aggressiveness of these lesions is related to prevailing histopathology and grading. We herein report a singular case of a stage IA combined atypical carcinoid with a large cell neuroendocrine and a lung scar cancer, its clinico-pathological workup, and its correlation with existing data in the literature.
Niccolò Daddi, Renato Colella, Michele Giansanti, Damiano Vinci, Mark Ragusa, Francesco Puma (2013). Unique case of combined stage Ia atypical carcinoid, large cell neuroendocrine carcinoma and adenocarcinoma of the lung. THORACIC CANCER, 4, 81-83 [10.1111/j.1759-7714.2012.00151.x].
Unique case of combined stage Ia atypical carcinoid, large cell neuroendocrine carcinoma and adenocarcinoma of the lung
DADDI, NICCOLO';
2013
Abstract
Although the 2004 World Health Organization classification attempted to clarify the role of combined neuroendocrine tumors of the lung, these are yet to be clearly defined. Prob- lems concerning clinical behavior are a result of unclear pathophysiology, the limited number of published cases, and the heterogeneity of histotypes involved. The aggressiveness of these lesions is related to prevailing histopathology and grading. We herein report a singular case of a stage IA combined atypical carcinoid with a large cell neuroendocrine and a lung scar cancer, its clinico-pathological workup, and its correlation with existing data in the literature.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
