This work aims at preparing new castor oil-derived polyesters with antibacterial activity. Ricinoleic acid and 10-undecenoic acid, derived from castor oil, were successfully used for this purpose. Firstly, an unsaturated homopolymer, derived from the self-polycondensation of ricinoleic acid, and its copolymers with poly(butylene succinate) were synthesized and resulted to be characterized by a remarkable biocidal activity against Staphilococcus aureus and a medium efficiency against Escherichia coli. Secondly, a PE-like aliphatic polyester, the poly(hexamethylene succinate), has been modified at the chain ends with the presence of unsaturated units of 10-undecenoate. This polymer was characterized by a low biocidal activity, mainly against Gram-positive bacteria. Furthermore, for both these polymeric systems the presence of the double bonds has been successfully exploited to covalently link an antimicrobial molecule, a vinyl imidazolium salt, which significantly improved the biocidal performances of the final polymers. Therefore, a general method to link molecules to the double bonds of PRA and undecenoate units and to insert new specific functionalites to the castor-oil derived polyesters is here developed.

Synthesis of castor oil-derived polyesters with antimicrobial activity / Grazia Totaro; Letizia Cruciani; Micaela Vannini; Giuseppe Mazzola; Diana Di Gioia; Annamaria Celli; Laura Sisti. - In: EUROPEAN POLYMER JOURNAL. - ISSN 0014-3057. - STAMPA. - 56:(2014), pp. 174-184. [10.1016/j.europolymj.2014.04.018]

Synthesis of castor oil-derived polyesters with antimicrobial activity

TOTARO, GRAZIA;CRUCIANI, LETIZIA;VANNINI, MICAELA;MAZZOLA, GIUSEPPE;DI GIOIA, DIANA;CELLI, ANNAMARIA;SISTI, LAURA
2014

Abstract

This work aims at preparing new castor oil-derived polyesters with antibacterial activity. Ricinoleic acid and 10-undecenoic acid, derived from castor oil, were successfully used for this purpose. Firstly, an unsaturated homopolymer, derived from the self-polycondensation of ricinoleic acid, and its copolymers with poly(butylene succinate) were synthesized and resulted to be characterized by a remarkable biocidal activity against Staphilococcus aureus and a medium efficiency against Escherichia coli. Secondly, a PE-like aliphatic polyester, the poly(hexamethylene succinate), has been modified at the chain ends with the presence of unsaturated units of 10-undecenoate. This polymer was characterized by a low biocidal activity, mainly against Gram-positive bacteria. Furthermore, for both these polymeric systems the presence of the double bonds has been successfully exploited to covalently link an antimicrobial molecule, a vinyl imidazolium salt, which significantly improved the biocidal performances of the final polymers. Therefore, a general method to link molecules to the double bonds of PRA and undecenoate units and to insert new specific functionalites to the castor-oil derived polyesters is here developed.
2014
Synthesis of castor oil-derived polyesters with antimicrobial activity / Grazia Totaro; Letizia Cruciani; Micaela Vannini; Giuseppe Mazzola; Diana Di Gioia; Annamaria Celli; Laura Sisti. - In: EUROPEAN POLYMER JOURNAL. - ISSN 0014-3057. - STAMPA. - 56:(2014), pp. 174-184. [10.1016/j.europolymj.2014.04.018]
Grazia Totaro; Letizia Cruciani; Micaela Vannini; Giuseppe Mazzola; Diana Di Gioia; Annamaria Celli; Laura Sisti
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/287913
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