We investigated the serotonin transporter gene (5-HTTLPR) in the functioning of euthymic patients with mood disorders (n = 285) and healthy controls (n = 94). The 5-HTTLPR genotype showed marginal associations with working, familial and social adjustment, with marked differences between controls and patients. Because of the exploratory nature of our analyses, all results should be viewed with caution. However, we observed how the s/s variant, commonly associated with detrimental effects, could be beneficial in specific areas of social adjustment. © 2005 Elsevier Ireland Ltd. All rights reserved.
Serretti A., Mandelli L., Lorenzi C., Smeraldi E. (2005). Social adjustment could be associated with the serotonin transporter gene in remitted patients with mood disorders and healthy subjects. PSYCHIATRY RESEARCH, 134, 191-194 [10.1016/j.psychres.2005.01.006].
Social adjustment could be associated with the serotonin transporter gene in remitted patients with mood disorders and healthy subjects
SERRETTI, ALESSANDRO;MANDELLI, LAURA;
2005
Abstract
We investigated the serotonin transporter gene (5-HTTLPR) in the functioning of euthymic patients with mood disorders (n = 285) and healthy controls (n = 94). The 5-HTTLPR genotype showed marginal associations with working, familial and social adjustment, with marked differences between controls and patients. Because of the exploratory nature of our analyses, all results should be viewed with caution. However, we observed how the s/s variant, commonly associated with detrimental effects, could be beneficial in specific areas of social adjustment. © 2005 Elsevier Ireland Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
