The ultrastructural features of layer II synapses in the perirhinal cortex of adult (4-6 month-old) and old (25-27 month-old) rats exposed to a 6-session object-recognition visual training were investigated by morphometric methods. The comparative analysis showed a higher synaptic numeric density, a lower synaptic average area and a lower percentage of megasynapses (S>0.5 μm2) in old trained rats vs. controls, and a higher percentage of small (S<0.15 μm2) junctions in adult trained rats vs. controls. The more marked synaptic remodelling underlying memory consolidation in the perirhinal cortex of old rats might reflect a pre-existing lower dynamic status.

Platano D., Bertoni-Freddari C., Fattoretti P., Giorgetti B., Grossi Y, Balietti M., et al. (2006). Structural synaptic remodelling in the perirhinal cortex of adult and old rats following object-recognition visual training. REJUVENATION RESEARCH, 9(1), 102-106 [10.1089/rej.2006.9.102].

Structural synaptic remodelling in the perirhinal cortex of adult and old rats following object-recognition visual training

PLATANO, DANIELA;BALIETTI, MARTA;AICARDI, GIORGIO
2006

Abstract

The ultrastructural features of layer II synapses in the perirhinal cortex of adult (4-6 month-old) and old (25-27 month-old) rats exposed to a 6-session object-recognition visual training were investigated by morphometric methods. The comparative analysis showed a higher synaptic numeric density, a lower synaptic average area and a lower percentage of megasynapses (S>0.5 μm2) in old trained rats vs. controls, and a higher percentage of small (S<0.15 μm2) junctions in adult trained rats vs. controls. The more marked synaptic remodelling underlying memory consolidation in the perirhinal cortex of old rats might reflect a pre-existing lower dynamic status.
2006
Platano D., Bertoni-Freddari C., Fattoretti P., Giorgetti B., Grossi Y, Balietti M., et al. (2006). Structural synaptic remodelling in the perirhinal cortex of adult and old rats following object-recognition visual training. REJUVENATION RESEARCH, 9(1), 102-106 [10.1089/rej.2006.9.102].
Platano D.; Bertoni-Freddari C.; Fattoretti P.; Giorgetti B.; Grossi Y; Balietti M.; Casoli T.; Di Stefano G.; Aicardi G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/27283
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