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EnglishSeveral studies have demonstrated the presence of actively replicating human endogenous retroviruses associated with various autoimmune disorders (Perron and Seigneurin, 1999; Portis, 2002), in particular, Sjögrens's syndrome, rheumatoid arthritis, type 1 or insulin-dependent diabetes mellitus, multiple sclerosis, systemic lupus erythematosus, and systemic sclerosis. Serum antibodies specific for human intracisternal A-type particles (HIAP), a human endogenous retrovirus recognized by monoclonal antibody against HIV-1 p24 capsid protein (Garry et al, 1990), have been detected significantly in association with primary biliary cirrhosis (Mason et al, 1998) and systemic sclerosis (La Placa et al, 2004).
| Titolo: | Serum antibodies against human intracisternal A-type particle (HIAP) endogenous retrovirus in Alopecia areata patients: a hallmark of autoimmune disease? |
| Autore/i: | LA PLACA, MICHELANGELO; VITONE, FRANCESCA; BIANCHI, TOMMASO; VINCENZI, COLOMBINA; GIBELLINI, DAVIDE; RE, MARIA CARLA; TOSTI, ANTONELLA |
| Autore/i Unibo: | |
| Anno: | 2004 |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/j.0022-202X.2004.23216.x |
| Abstract: | Several studies have demonstrated the presence of actively replicating human endogenous retroviruses associated with various autoimmune disorders (Perron and Seigneurin, 1999; Portis, 2002), in particular, Sjögrens's syndrome, rheumatoid arthritis, type 1 or insulin-dependent diabetes mellitus, multiple sclerosis, systemic lupus erythematosus, and systemic sclerosis. Serum antibodies specific for human intracisternal A-type particles (HIAP), a human endogenous retrovirus recognized by monoclonal antibody against HIV-1 p24 capsid protein (Garry et al, 1990), have been detected significantly in association with primary biliary cirrhosis (Mason et al, 1998) and systemic sclerosis (La Placa et al, 2004). |
| Data prodotto definitivo in UGOV: | 2005-09-28 17:51:08 |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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http://hdl.handle.net/11585/2718
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