Canine distemper virus (CDV) a member of the Morbillivirus genus of the family Paramyxoviridae, is a highly infectious and an acknowledged lethal pathogen of many carnivores. The disease is controlled by vaccination but an increasing number of distemper cases has been recorded even in vaccinated dogs all over the world and the affected animals can display catharral and or neurological symptoms. At present, there is no specific therapy, even if there is an increasing demand for one from the dog owners. For this reason the research on antiviral compounds against distemper is aimed at finding active molecules to treat the infection. Ribavirin (1-
Scagliarini A., Vaccari F., Gallina L., Dal Pozzo F., Prosperi S. (2006). In vitro evaluation of antiviral activity of ribavirin against canine distemper virus. VETERINARY RESEARCH COMMUNICATIONS, 30 (1), 269-272 [10.1007/s11259-006-0058-0].
In vitro evaluation of antiviral activity of ribavirin against canine distemper virus
SCAGLIARINI, ALESSANDRA;VACCARI, FRANCESCA;GALLINA, LAURA;DAL POZZO, FABIANA;PROSPERI, SANTINO
2006
Abstract
Canine distemper virus (CDV) a member of the Morbillivirus genus of the family Paramyxoviridae, is a highly infectious and an acknowledged lethal pathogen of many carnivores. The disease is controlled by vaccination but an increasing number of distemper cases has been recorded even in vaccinated dogs all over the world and the affected animals can display catharral and or neurological symptoms. At present, there is no specific therapy, even if there is an increasing demand for one from the dog owners. For this reason the research on antiviral compounds against distemper is aimed at finding active molecules to treat the infection. Ribavirin (1-I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
