Proline and pyrrolidine derivatives (Hayashi– Jørgensen catalysts) are considered “work horses” in organocatalysis. This report describes a new effective ferrocenyl pyrrolidine catalyst that is able to perform well in benchmark organocatalytic reactions (see figure). The ferrocene moiety controls the conformational space and a simple alkyl group effectively covers a face of the derived enamine. This new framework can find applications in organocatalysis, and in general, in new ligand design

A Rational Approach Towards a New Ferrocenyl Pyrrolidine for Stereoselective Enamine Catalysis / Petruzziello D.; Stenta M.; Mazzanti A.; Cozzi P.G.. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 19:24(2013), pp. 7696-7700. [10.1002/chem.201300959]

A Rational Approach Towards a New Ferrocenyl Pyrrolidine for Stereoselective Enamine Catalysis

MAZZANTI, ANDREA;COZZI, PIER GIORGIO
2013

Abstract

Proline and pyrrolidine derivatives (Hayashi– Jørgensen catalysts) are considered “work horses” in organocatalysis. This report describes a new effective ferrocenyl pyrrolidine catalyst that is able to perform well in benchmark organocatalytic reactions (see figure). The ferrocene moiety controls the conformational space and a simple alkyl group effectively covers a face of the derived enamine. This new framework can find applications in organocatalysis, and in general, in new ligand design
2013
A Rational Approach Towards a New Ferrocenyl Pyrrolidine for Stereoselective Enamine Catalysis / Petruzziello D.; Stenta M.; Mazzanti A.; Cozzi P.G.. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 19:24(2013), pp. 7696-7700. [10.1002/chem.201300959]
Petruzziello D.; Stenta M.; Mazzanti A.; Cozzi P.G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/257878
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