The rotational spectra of several isotopologues of the 1:1 complex between the inhaled anesthetic isoflurane and water have been recorded and analyzed by using Fourier transform microwave spectroscopy. The rotational spectrum showed a single rotamer, corresponding to the configuration in which the most stable conformer of isolated isoflurane is linked to the water molecule through an almost linear CH···O weak hydrogen bond. All transitions display a hyperfine structure due to the 35Cl (or 37Cl) nuclear quadrupole effects.
How Water Interacts with Halogenated Anesthetics: The Rotational Spectrum of Isoflurane-Water / Qian Gou;Gang Feng;Luca Evangelisti;Montserrat Vallejo-López;Lorenzo Spada;Alberto Lesarri;Emilio J. Cocinero;Walther Caminati. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 20:(2014), pp. 1980-1984. [10.1002/chem.201303724]
How Water Interacts with Halogenated Anesthetics: The Rotational Spectrum of Isoflurane-Water
GOU, QIAN;FENG, GANG;EVANGELISTI, LUCA;SPADA, LORENZO;CAMINATI, WALTHER
2014
Abstract
The rotational spectra of several isotopologues of the 1:1 complex between the inhaled anesthetic isoflurane and water have been recorded and analyzed by using Fourier transform microwave spectroscopy. The rotational spectrum showed a single rotamer, corresponding to the configuration in which the most stable conformer of isolated isoflurane is linked to the water molecule through an almost linear CH···O weak hydrogen bond. All transitions display a hyperfine structure due to the 35Cl (or 37Cl) nuclear quadrupole effects.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
