The authors developed a gold-cat- alyzed hydroamination followed by an asymmetric nucleophilic allylic substitution cascade to access oxazino[4,3- a ]indoles in good yields and enantio- The authors developed a gold-cat- alyzed hydroamination followed by an asymmetric nucleophilic allylic substitution cascade to access oxazino[4,3- a ]indoles in good yields and enantio- selectivities. Owing to pharmacologically active in- dole alkaloids, this rapid synthesis and asymmet- ric decoration of the polycyclic indolyl core is highly important

Indole chemistry continues to gain credit within organic synthesis owing to the ubiquitous presence of this heteroaromatic ring in pharmaceuticals, agrochemicals, and organic functional material science. Over the past few years, metal and metal-free catalysis has played a major role in the area, contributing to the development of a number of sustainable procedures for both synthesis and asymmetric decoration of the indolyl core.