Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.
Mechanisms of Obesity-induced Gastrointestinal Neoplasia / José O. Alemán;Leonardo H. Eusebi;Luigi Ricciardiello;Kavish Patidar;Arun J. Sanyal;Peter R. Holt. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - STAMPA. - 146:2(2014), pp. 357-373. [10.1053/j.gastro.2013.11.051]
Mechanisms of Obesity-induced Gastrointestinal Neoplasia
EUSEBI, LEONARDO HENRY UMBERTO;RICCIARDIELLO, LUIGI;
2014
Abstract
Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
