The Povarov reaction provides a straightforward and modular entry to 1,2,3,4-tetrahydroquinolines (THQs). Despite its importance, it was only very recently that several highly efficient catalytic asymmetric protocols for this reaction have been developed,as summarized in this review which falls on the 50th anniversary of Povarov’s pioneering disclosure. Furthermore, this review collects and critically discusses the interrupted versions of the reaction,often featuring intriguing and still unclear mechanicistic pathways.

Mariafrancesca Fochi, Lorenzo Caruana, Luca Bernardi (2014). Catalytic Asymmetric Aza-Diels–Alder Reactions: The Povarov Cycloaddition Reaction. SYNTHESIS, 46(2), 135-157 [10.1055/s-0033-1338581].

Catalytic Asymmetric Aza-Diels–Alder Reactions: The Povarov Cycloaddition Reaction

FOCHI, MARIAFRANCESCA;CARUANA, LORENZO;BERNARDI, LUCA
2014

Abstract

The Povarov reaction provides a straightforward and modular entry to 1,2,3,4-tetrahydroquinolines (THQs). Despite its importance, it was only very recently that several highly efficient catalytic asymmetric protocols for this reaction have been developed,as summarized in this review which falls on the 50th anniversary of Povarov’s pioneering disclosure. Furthermore, this review collects and critically discusses the interrupted versions of the reaction,often featuring intriguing and still unclear mechanicistic pathways.
2014
Mariafrancesca Fochi, Lorenzo Caruana, Luca Bernardi (2014). Catalytic Asymmetric Aza-Diels–Alder Reactions: The Povarov Cycloaddition Reaction. SYNTHESIS, 46(2), 135-157 [10.1055/s-0033-1338581].
Mariafrancesca Fochi; Lorenzo Caruana; Luca Bernardi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/219277
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