The selective activation/functionalization of benzhydryl CACHTUNGTRENUNG(sp3)H bonds is documented. The gold complex XPhosAuNTf2 turned out to be an efficient catalyst (5 mol%) to transform readily available propargylic esters into di- or trisubstituted naphthalenes in high yield. A 1,5-hydride shift is postulated as the key step of the cascade reaction sequence.
Gianpiero Cera, Michel Chiarucci, Federico Dosi, Marco Bandini (2013). Gold(I)-Catalyzed Functionalization of Benzhydryl C-(sp3)H Bonds. ADVANCED SYNTHESIS & CATALYSIS, 355, 2227-2231 [10.1002/adsc.201300525].
Gold(I)-Catalyzed Functionalization of Benzhydryl C-(sp3)H Bonds
CERA, GIANPIERO;CHIARUCCI, MICHEL;BANDINI, MARCO
2013
Abstract
The selective activation/functionalization of benzhydryl CACHTUNGTRENUNG(sp3)H bonds is documented. The gold complex XPhosAuNTf2 turned out to be an efficient catalyst (5 mol%) to transform readily available propargylic esters into di- or trisubstituted naphthalenes in high yield. A 1,5-hydride shift is postulated as the key step of the cascade reaction sequence.File in questo prodotto:
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