The selective activation/functionalization of benzhydryl CACHTUNGTRENUNG(sp3)H bonds is documented. The gold complex XPhosAuNTf2 turned out to be an efficient catalyst (5 mol%) to transform readily available propargylic esters into di- or trisubstituted naphthalenes in high yield. A 1,5-hydride shift is postulated as the key step of the cascade reaction sequence.

Gold(I)-Catalyzed Functionalization of Benzhydryl C-(sp3)H Bonds

CERA, GIANPIERO;CHIARUCCI, MICHEL;BANDINI, MARCO
2013

Abstract

The selective activation/functionalization of benzhydryl CACHTUNGTRENUNG(sp3)H bonds is documented. The gold complex XPhosAuNTf2 turned out to be an efficient catalyst (5 mol%) to transform readily available propargylic esters into di- or trisubstituted naphthalenes in high yield. A 1,5-hydride shift is postulated as the key step of the cascade reaction sequence.
2013
Gianpiero Cera; Michel Chiarucci; Federico Dosi; Marco Bandini
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/193529
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