Gold nanoparticles coated with fluorinated ligands (F-MPCs) present features suitable for F-19 MRI as observed from phantom experiments. Cellular uptake, by HeLa cells, and toxicity of fluorescent dye-decorated F-MPCs are presented together with their ability to bind hydrophobic molecules allowing for a potential combination of targeting, delivery and imaging features.
Gold nanoparticles protected by fluorinated ligands for F-19 MRI / M. Boccalon; P. Franchi; M. Lucarini; J.J. Delgado; F. Sousa; F. Stellacci; I. Zucca; A. Scotti; R. Spreafico; P. Pengo; L. Pasquato. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - STAMPA. - 49:(2013), pp. 8794-8796. [10.1039/c3cc44572k]
Gold nanoparticles protected by fluorinated ligands for F-19 MRI
FRANCHI, PAOLA;LUCARINI, MARCO;
2013
Abstract
Gold nanoparticles coated with fluorinated ligands (F-MPCs) present features suitable for F-19 MRI as observed from phantom experiments. Cellular uptake, by HeLa cells, and toxicity of fluorescent dye-decorated F-MPCs are presented together with their ability to bind hydrophobic molecules allowing for a potential combination of targeting, delivery and imaging features.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
