Spindle cell sarcoma of bone arising from a non-ossifying fibroma: A case report

The majority of malignant bone lesions, and spindle cell sarcoma of bone is no exception, arise spontaneously. Less frequently, they may be secondary to other conditions like radiation therapy, bone pathologies like Paget's disease, bone infarct, aseptic necrosis and many benign tumors or tumor like bone conditions like metaphyseal fibrous defect (MFD), giant cell tumor (GCT), osteochondroma, chondroma and others.1 This work describes a very rare case of sarcoma of bone arisen in the same area of a benign lesion, diagnosed occasionally ten years ago, which has not undergone previously medical, radiotherapic or surgical treatment.