Definitions and classification of dyspepsia: pH, Helicobacter pylori, non-steroidal anti-inflammatory drugs--should we include gastro-oesophageal reflux disease?

Workshop Consensus on Clinical Management Issues How should patients who complain of dyspepsia be managed? Patients with dyspepsia should be considered based upon their predominant symptoms, which may increase the probability of ulcer disease vs. oesophagitis in the respective subgroups. Testing for H. pylori infection and treatment in those with non-investigated dyspepsia should be considered in those with predominant epigastric pain. Although some patients with functional dyspepsia may benefit from H. pylori cure, PPI therapy is still regarded as the strategy of first choice, particularly in those with reflux symptoms. In patients with dyspepsia, are NSAIDs and aspirin frequent causes? Only 41% of workshop participants agreed, albeit with reservation that non-steroidal anti-inflammatory drugs (NSAIDs) and aspirin are frequent causes of dyspepsia. About 59% disagreed 41% of participants with reservation and 18% with strong disagreement.