Gastric acidification reduces gastrin release and consequently hydrochloric acid secretion, but its long term effect has not been enough studied. The number of enterochromaffin-like and parietal cells was evaluated in 60 weaning pigs, using histochemical and immunohistochemical techniques. Pigs supplemented with 12 g/kg calcium formate for 7 or 8 days had a relevant reduction of parietal cells, compared to control ones. With fat-protected formate supplementation (same dose) this reduction was not observed. The number of enterochromaffin-like cells showed a similar trend, but not statistically significant. Effects on gastric morphology should be controlled when a diet supplemented with calcium formate was ceased. Furthermore a reduction of the number of parietal cells could impair the absorption of vitamin B12 due to a reduced secretion of intrinsic factor by this type of cells.
Mazzoni M., Lalatta Costerbosa G., Casini L., Petrosino G., Trevisi P., De Filippi S., et al. (2004). LA MORFOLOGIA DELLO STOMACO COME PARAMETRO DI VALUTAZIONE DELL’IMPIEGO DI ACIDIFICANTI NELLA DIETA DEL SUINO IN SVEZZAMENTO. s.l : s.n.
LA MORFOLOGIA DELLO STOMACO COME PARAMETRO DI VALUTAZIONE DELL’IMPIEGO DI ACIDIFICANTI NELLA DIETA DEL SUINO IN SVEZZAMENTO
MAZZONI, MAURIZIO;LALATTA COSTERBOSA, GIOVANNA;CASINI, LUISA;TREVISI, PAOLO;DE FILIPPI, SARA;BOSI, PAOLO
2004
Abstract
Gastric acidification reduces gastrin release and consequently hydrochloric acid secretion, but its long term effect has not been enough studied. The number of enterochromaffin-like and parietal cells was evaluated in 60 weaning pigs, using histochemical and immunohistochemical techniques. Pigs supplemented with 12 g/kg calcium formate for 7 or 8 days had a relevant reduction of parietal cells, compared to control ones. With fat-protected formate supplementation (same dose) this reduction was not observed. The number of enterochromaffin-like cells showed a similar trend, but not statistically significant. Effects on gastric morphology should be controlled when a diet supplemented with calcium formate was ceased. Furthermore a reduction of the number of parietal cells could impair the absorption of vitamin B12 due to a reduced secretion of intrinsic factor by this type of cells.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
