Linear atrophoderma of Moulin is a rare skin condition, fist described in 1992 by Moulin et al. who reported 5 patients affected by unilateral, hyperpigmented, depressed plaques self limited along Blaschko’s lines on the trunk and extremites, without any evidence of long-term progression. The main histologic finging was a basal hyperpigmentation, while other epidermal layers and dermis were normal, including normal-appearing collagen and elastic fibers. Thus, the clinical atrophy was initially linked to an alteration of the subcutaneous tissue, but a deep biopsy on both the affected and controlateral sides was originally not performed. Moulin et al. suggested the term “blaschkose” in opposition to “ blaschkitis” with an inflammatory and acquired significance. Later, this skin desease was named “LAM” by Baumman et al. who classified this disease as belonging to the group of acquired linear dermatoses following BL and thought LAM as a variant of prpogressive atrophoderma of Pasini and Pierini. In the literature, the clinical and histopathological criteria for the diagnosis of LAM heve been expanded in the last years and cases with different clinical and histological features have been classified as LAM

atrophoderma following the lines of blaschko: an interesting diagnostic dilemma. Linear atrophoderma of moulin, blaschkolinear atrophoderma of pasini and pierini or linear morphea?

PATRIZI, ANNALISA;NERI, IRIA;PAZZAGLIA, MASSIMILIANO;
2013

Abstract

Linear atrophoderma of Moulin is a rare skin condition, fist described in 1992 by Moulin et al. who reported 5 patients affected by unilateral, hyperpigmented, depressed plaques self limited along Blaschko’s lines on the trunk and extremites, without any evidence of long-term progression. The main histologic finging was a basal hyperpigmentation, while other epidermal layers and dermis were normal, including normal-appearing collagen and elastic fibers. Thus, the clinical atrophy was initially linked to an alteration of the subcutaneous tissue, but a deep biopsy on both the affected and controlateral sides was originally not performed. Moulin et al. suggested the term “blaschkose” in opposition to “ blaschkitis” with an inflammatory and acquired significance. Later, this skin desease was named “LAM” by Baumman et al. who classified this disease as belonging to the group of acquired linear dermatoses following BL and thought LAM as a variant of prpogressive atrophoderma of Pasini and Pierini. In the literature, the clinical and histopathological criteria for the diagnosis of LAM heve been expanded in the last years and cases with different clinical and histological features have been classified as LAM
annalisa patrizi; michela venturi; iria neri; massimiliano pazzaglia; beatrice passarini
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/165445
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