Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, that bears remarkable cytomorphological resemblance to endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a ten-year-old female dog is reported. Multiple whitish-grey nodules (1-5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating polygonal or ovoid cells with an abundant eosinophilic glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.
Morini M., Bettini G., Morandi F., Burdisso R., Marcato P.S. (2006). DECIDUOID PERITONEAL MESOTHELIOMA IN A DOG. VETERINARY PATHOLOGY, 43, 198-201 [10.1354/vp.43-2-198].
DECIDUOID PERITONEAL MESOTHELIOMA IN A DOG
MORINI, MARIA;BETTINI, GIULIANO;MARCATO, PAOLO STEFANO
2006
Abstract
Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, that bears remarkable cytomorphological resemblance to endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a ten-year-old female dog is reported. Multiple whitish-grey nodules (1-5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating polygonal or ovoid cells with an abundant eosinophilic glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
