new valuable catalytic protocol for the preparation of synthetically useful beta-indolyl nitro compounds bearing benzhydryl stereocenters is presented. The combined use of catalytic amounts of a commercially available chiral [SalenAlCl] complex and pyridine allowed, for the Friedel-Crafts alkylation reaction of indoles with aromatic nitro-olefins to be carried out in good yields and enantioselectivity (up to 63% ee). (c) 2005 Wiley-Liss, Inc. Chirality 17:522-529, 2005.

Catalytic enantioselective addition of indoles to aryl-nitroalkenes. Effective route to enantiomerically enriched tryptamine precursors

BANDINI, MARCO;GARELLI, ANDREA;TOMMASI, SIMONA;UMANI RONCHI, ACHILLE
2005

Abstract

new valuable catalytic protocol for the preparation of synthetically useful beta-indolyl nitro compounds bearing benzhydryl stereocenters is presented. The combined use of catalytic amounts of a commercially available chiral [SalenAlCl] complex and pyridine allowed, for the Friedel-Crafts alkylation reaction of indoles with aromatic nitro-olefins to be carried out in good yields and enantioselectivity (up to 63% ee). (c) 2005 Wiley-Liss, Inc. Chirality 17:522-529, 2005.
M. Bandini; A. Garelli; M. Rovinetti; S. Tommasi; A. Umani-Ronchi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/15114
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