We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4–5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.
Ilaria M. Saracino, Cristina Zaccaro, Giovanna Lo Re, Dino Vaira, John Holton (2013). The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori. ANTIBIOTICS, 2, 265-273 [10.3390/antibiotics2020265].
The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
SARACINO, ILARIA MARIA;ZACCARO, CRISTINA;VAIRA, BERARDINO;
2013
Abstract
We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4–5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.| File | Dimensione | Formato | |
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