Disgust for contaminating objects (core disgust), immoral behaviors (moral disgust) and unsavory others (interpersonal disgust), have been assumed to be closely related. It is not clear, however, whether different forms of disgust are mediated by overlapping or specific neural substrates. We report that 10 patients with damage to the ventromedial prefrontal cortex (vmPFC) avoided behaviors that normally elicit interpersonal disgust (e.g. using the scarf of a busker) less frequently than healthy and brain-damaged controls, whereas they avoided core and moral disgust elicitors at normal rates. These results indicate that different forms of disgust are dissociated neurally. We propose that the vmPFC is causally (and selectively) involved in mediating interpersonal disgust, shaping patterns of social avoidance and approach.

Ciaramelli E, Sperotto RG, Mattioli F, di Pellegrino G. (2013). Damage to the ventromedial prefrontal cortex reduces interpersonal disgust. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 8, 171-180 [10.1093/scan/nss087].

Damage to the ventromedial prefrontal cortex reduces interpersonal disgust

CIARAMELLI, ELISA;DI PELLEGRINO, GIUSEPPE
2013

Abstract

Disgust for contaminating objects (core disgust), immoral behaviors (moral disgust) and unsavory others (interpersonal disgust), have been assumed to be closely related. It is not clear, however, whether different forms of disgust are mediated by overlapping or specific neural substrates. We report that 10 patients with damage to the ventromedial prefrontal cortex (vmPFC) avoided behaviors that normally elicit interpersonal disgust (e.g. using the scarf of a busker) less frequently than healthy and brain-damaged controls, whereas they avoided core and moral disgust elicitors at normal rates. These results indicate that different forms of disgust are dissociated neurally. We propose that the vmPFC is causally (and selectively) involved in mediating interpersonal disgust, shaping patterns of social avoidance and approach.
2013
Ciaramelli E, Sperotto RG, Mattioli F, di Pellegrino G. (2013). Damage to the ventromedial prefrontal cortex reduces interpersonal disgust. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 8, 171-180 [10.1093/scan/nss087].
Ciaramelli E; Sperotto RG; Mattioli F; di Pellegrino G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/143851
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