NCOA4 is widely expressed in several tissues, including testis, adrenal and thyroid glands, thymus, prostate. A truncated NCOA4 corresponding to the beta isoform is fused to RET exon 12 and is aberrantly expressed in papillary thyroid carcinoma as a consequence of intrachromosomal rearrangements at 10q11.2 (RET/NCOA4).
D. de Biase, L. Morandi, G. Tallini (2009). NCOA4 (Nuclear Receptor Coactivator 4). ATLAS OF GENETICS AND CYTOGENETICS IN ONCOLOGY AND HAEMATOLOGY, 13, 654-656.
NCOA4 (Nuclear Receptor Coactivator 4)
DE BIASE, DARIO;MORANDI, LUCA;TALLINI, GIOVANNI
2009
Abstract
NCOA4 is widely expressed in several tissues, including testis, adrenal and thyroid glands, thymus, prostate. A truncated NCOA4 corresponding to the beta isoform is fused to RET exon 12 and is aberrantly expressed in papillary thyroid carcinoma as a consequence of intrachromosomal rearrangements at 10q11.2 (RET/NCOA4).File in questo prodotto:
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