The catalytic properties of chitosan aerogel for the direct asymmetric aldol reaction in water assisted by various surfac- tants and acid co-catalysts have been evaluated by em- ploying a range of donor and acceptor systems. A beneficial effect on both the yields and enantioselectivities was observed, and the combination of surfactants and acid co-catalysts has proven particularly useful in the case of heterocyclic ketone donors.
C. Gioia, A. Ricci, L. Bernardi, K. Bourahla, N. Tanchoux, M. Robitzer, et al. (2013). Chitosan Aerogel Beads as a Heterogeneous Organocatalyst for the Asymmetric Aldol Reaction in the Presence of Water: an Assessment of the Effect of Additives. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 588-594 [10.1002/ejoc.201201187].
Chitosan Aerogel Beads as a Heterogeneous Organocatalyst for the Asymmetric Aldol Reaction in the Presence of Water: an Assessment of the Effect of Additives
GIOIA, CLAUDIO;RICCI, ALFREDO MARCO;BERNARDI, LUCA;
2013
Abstract
The catalytic properties of chitosan aerogel for the direct asymmetric aldol reaction in water assisted by various surfac- tants and acid co-catalysts have been evaluated by em- ploying a range of donor and acceptor systems. A beneficial effect on both the yields and enantioselectivities was observed, and the combination of surfactants and acid co-catalysts has proven particularly useful in the case of heterocyclic ketone donors.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
