The first example of a catalytic asymmetric vinylogous Povarov reaction is presented. 1-N-Acylamino-1,3-butadienes react selectively at their terminal double bond in the presence of a chiral phosphoric acid catalyst, delivering highly enantioenriched 1,2,3,4- tetrahydroquinolines bearing a synthetically versatile enecarbamate group at the 4-position.
Catalytic highly enantioselective vinylogous Povarov reaction / L. Caruana; M. Fochi; S. Ranieri; A. Mazzanti; L. Bernardi. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - STAMPA. - 49:(2013), pp. 880-882. [10.1039/c2cc38002a]
Catalytic highly enantioselective vinylogous Povarov reaction
CARUANA, LORENZO;FOCHI, MARIAFRANCESCA;RANIERI, SILVIA;MAZZANTI, ANDREA;BERNARDI, LUCA
2013
Abstract
The first example of a catalytic asymmetric vinylogous Povarov reaction is presented. 1-N-Acylamino-1,3-butadienes react selectively at their terminal double bond in the presence of a chiral phosphoric acid catalyst, delivering highly enantioenriched 1,2,3,4- tetrahydroquinolines bearing a synthetically versatile enecarbamate group at the 4-position.File in questo prodotto:
Eventuali allegati, non sono esposti
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
