Hypertensive disorders complicate approximately 10- 20% of pregnancies and cover a spectrum of diffe- rent clinical pictures with varying impact on the health of mother and fetus. Among these pre-eclampsia (PE) represents the most severe form, being alone respon- sible for 15-20% of cases of maternal mortality and a major cause of perinatal mortality and morbi- dity. The clinical significance of hypertensive disorders in pregnancy is also linked to the possibility of serious maternal complications represented by HELLP syn- drome (characterized by hemolysis, elevated liver fun- ction and low platelet count), eclampsia and dissemi- nated intravascular coagulation (DIC). Laboratory monitoring of indices (blood count, pla- telet count, liver function, renal function, uric acid, LDH, proteinuria, etc.), associated with the evaluation of the patient’s clinical condition, is the only tool available to the clinical diagnosis and subsequent management of various conditions, with particular reference to the ti- ming of childbirth, the only real treatment of PE. Key-words: pregnancy, gestosis, preeclamsia, laboratory findings, HELLP syndrome.
A. Curti, G. Simonazzi, N. Rizzo (2010). Preeclampsia. LA RIVISTA ITALIANA DELLA MEDICINA DI LABORATORIO, 6(2), 111-114.
Preeclampsia
SIMONAZZI, GIULIANA;RIZZO, NICOLA
2010
Abstract
Hypertensive disorders complicate approximately 10- 20% of pregnancies and cover a spectrum of diffe- rent clinical pictures with varying impact on the health of mother and fetus. Among these pre-eclampsia (PE) represents the most severe form, being alone respon- sible for 15-20% of cases of maternal mortality and a major cause of perinatal mortality and morbi- dity. The clinical significance of hypertensive disorders in pregnancy is also linked to the possibility of serious maternal complications represented by HELLP syn- drome (characterized by hemolysis, elevated liver fun- ction and low platelet count), eclampsia and dissemi- nated intravascular coagulation (DIC). Laboratory monitoring of indices (blood count, pla- telet count, liver function, renal function, uric acid, LDH, proteinuria, etc.), associated with the evaluation of the patient’s clinical condition, is the only tool available to the clinical diagnosis and subsequent management of various conditions, with particular reference to the ti- ming of childbirth, the only real treatment of PE. Key-words: pregnancy, gestosis, preeclamsia, laboratory findings, HELLP syndrome.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


