The crystal structures of four crystal forms of rifaximin, named a, b, d and e, have been elucidated by a combination of single crystal and powder diffraction experiments with synchrotron and X-ray sources. The crystal structures of the d and e forms have been determined from powder diffraction data alone. Hot stage microscopy has also been of paramount importance in the understanding of the b -> a conversion process.
The structure–property relationship of four crystal forms of rifaximin / D. Braga; F. Grepioni; L. Chelazzi; M. Campana; D. Confortini; G. C. Viscomi. - In: CRYSTENGCOMM. - ISSN 1466-8033. - ELETTRONICO. - 14:(2012), pp. 6404-6411. [10.1039/c2ce25920f]
The structure–property relationship of four crystal forms of rifaximin
BRAGA, DARIO;GREPIONI, FABRIZIA;CHELAZZI, LAURA;
2012
Abstract
The crystal structures of four crystal forms of rifaximin, named a, b, d and e, have been elucidated by a combination of single crystal and powder diffraction experiments with synchrotron and X-ray sources. The crystal structures of the d and e forms have been determined from powder diffraction data alone. Hot stage microscopy has also been of paramount importance in the understanding of the b -> a conversion process.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
