A culturable microbiota less than 103CFU/ml is detectable in human normocholorydric stomach. Impaired gastric acid secretion, caused by chronic atrophic gastritis or proton pump inhibitors, allowed a bacterial gastric overgrowth with a culturable microbiota up to 107CFU/ml. Considering that Bifidobacteriaceae are components of the oral microbiota and that bacterial overgrowth in reduced gastric acid secretion can be related to colonization from upstream components of the alimentary tract, it is unexpected that most of the large scales studies recently conducted failed to detect members of Bifidobacteriaceae in subjects with stomach hypochlorydria.
Mattarelli P., Brandi G., Calabrese C., Fornari F., Prati G., Biavati B., et al. (2012). Bifidobacteriaceae usually colonize human hypochloridric stomach.
Bifidobacteriaceae usually colonize human hypochloridric stomach
MATTARELLI, PAOLA;BRANDI, GIOVANNI;CALABRESE, CARLO;BIAVATI, BRUNO;SGORBATI, BARBARA
2012
Abstract
A culturable microbiota less than 103CFU/ml is detectable in human normocholorydric stomach. Impaired gastric acid secretion, caused by chronic atrophic gastritis or proton pump inhibitors, allowed a bacterial gastric overgrowth with a culturable microbiota up to 107CFU/ml. Considering that Bifidobacteriaceae are components of the oral microbiota and that bacterial overgrowth in reduced gastric acid secretion can be related to colonization from upstream components of the alimentary tract, it is unexpected that most of the large scales studies recently conducted failed to detect members of Bifidobacteriaceae in subjects with stomach hypochlorydria.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
