Small-for-size syndrome in LDLT is associated with graft exposure to excessive portal perfusion. Prevention of graft overperfusion in LDLT can be achieved through intraoperative modulation of portal graft inflow. We report a successful LDLT utilising the left lobe with a GV/SLV of only 20%. A 43 year-old patient underwent to LDLT at our institution. During the anhepatic phase a porto-systemic shunt utilizing an interposition vein graft anastomosed between the right portal branch and the right hepatic vein was performed. After graft reperfusion splenectomy was also performed. Portal vein pressure, portal vein flow and hepatic artery flow were recorded. A decrease of portal vein pressure and flow was achieved, and the shunt was left in place. The recipient post-operative course was characterized by good graft function. Small-for-size syndrome by graft overperfusion can be successfully prevented by utilizing inflow modulation of the transplanted graft. This strategy can permit the use of left lobe in adult-to-adult living donor liver transplantation.

Living donor liver transplantation with left liver graft / M.Masetti;A.Siniscalchi;L.De Pietri;V.Braglia;F.Di Benedetto;N.Cautero;B.Begliomini;A.Romano;CM.Miller;G.Ramacciato;AD.Pinna. - In: AMERICAN JOURNAL OF TRANSPLANTATION. - ISSN 1600-6135. - STAMPA. - 4:(2004), pp. 1713-1716. [10.1111/j.1600-6143.2004.00548.x]

Living donor liver transplantation with left liver graft.

SINISCALCHI, ANTONIO;PINNA, ANTONIO DANIELE
2004

Abstract

Small-for-size syndrome in LDLT is associated with graft exposure to excessive portal perfusion. Prevention of graft overperfusion in LDLT can be achieved through intraoperative modulation of portal graft inflow. We report a successful LDLT utilising the left lobe with a GV/SLV of only 20%. A 43 year-old patient underwent to LDLT at our institution. During the anhepatic phase a porto-systemic shunt utilizing an interposition vein graft anastomosed between the right portal branch and the right hepatic vein was performed. After graft reperfusion splenectomy was also performed. Portal vein pressure, portal vein flow and hepatic artery flow were recorded. A decrease of portal vein pressure and flow was achieved, and the shunt was left in place. The recipient post-operative course was characterized by good graft function. Small-for-size syndrome by graft overperfusion can be successfully prevented by utilizing inflow modulation of the transplanted graft. This strategy can permit the use of left lobe in adult-to-adult living donor liver transplantation.
2004
Living donor liver transplantation with left liver graft / M.Masetti;A.Siniscalchi;L.De Pietri;V.Braglia;F.Di Benedetto;N.Cautero;B.Begliomini;A.Romano;CM.Miller;G.Ramacciato;AD.Pinna. - In: AMERICAN JOURNAL OF TRANSPLANTATION. - ISSN 1600-6135. - STAMPA. - 4:(2004), pp. 1713-1716. [10.1111/j.1600-6143.2004.00548.x]
M.Masetti;A.Siniscalchi;L.De Pietri;V.Braglia;F.Di Benedetto;N.Cautero;B.Begliomini;A.Romano;CM.Miller;G.Ramacciato;AD.Pinna
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/123198
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 53
  • ???jsp.display-item.citation.isi??? 44
social impact