Background: The aim of our study was to test the aerostatic validity of a cyan-acrylic glue (Glubran 2 ), applied by means of a spray catheter, on an experimental pig model. Materials and Methods: 15 young pigs were divided into three study groups of 5 based on surgical techniques: (1) atypical pulmonary resection with mechanical suturing and reinforcement with continuous suturing; (2) resection of the pulmonary parenchyma with a cold scalpel, followed by local application of Glubran 2; (3) atypical pulmonary resection with mechanical suturing followed by application of Glubran 2. Results: The mean aerostasis time was calculated at 3.5 8 1.26 s. The histopathological analysis did not show any particular differences when comparing the effects of the treatments carried out with Glubran 2 spray glue and the standard treatments. No statistically significant differences were recorded in the short- and medium-term survival of pigs treated with Glubran 2 compared with the respective control groups. Conclusions: The application of Glubran 2 spray on wounds caused by pulmonary resections in pigs proved to have a rapid and effective influence for the purposes of aerostasis without significant differences in air losses and survivals.
Davoli F., Sellitri F., Brandolini J., Dolci G., Castagnoli A., Bedetti B., et al. (2009). USE OF COAGULANT SPRAY GLUE (GLUBRAN 2) FOR AEROSTATIC PURPOSES IN PULMONARY PARENCHYMA RESECTIONS IN PIGS: A PRELIMINARY STUDY. EUROPEAN SURGICAL RESEARCH, 43, 360-364 [10.1159/000248334].
USE OF COAGULANT SPRAY GLUE (GLUBRAN 2) FOR AEROSTATIC PURPOSES IN PULMONARY PARENCHYMA RESECTIONS IN PIGS: A PRELIMINARY STUDY
DAVOLI, FABIO;BRANDOLINI, JURY;DOLCI, GIAMPIERO;CASTAGNOLI, ANNA;STELLA, FRANCO
2009
Abstract
Background: The aim of our study was to test the aerostatic validity of a cyan-acrylic glue (Glubran 2 ), applied by means of a spray catheter, on an experimental pig model. Materials and Methods: 15 young pigs were divided into three study groups of 5 based on surgical techniques: (1) atypical pulmonary resection with mechanical suturing and reinforcement with continuous suturing; (2) resection of the pulmonary parenchyma with a cold scalpel, followed by local application of Glubran 2; (3) atypical pulmonary resection with mechanical suturing followed by application of Glubran 2. Results: The mean aerostasis time was calculated at 3.5 8 1.26 s. The histopathological analysis did not show any particular differences when comparing the effects of the treatments carried out with Glubran 2 spray glue and the standard treatments. No statistically significant differences were recorded in the short- and medium-term survival of pigs treated with Glubran 2 compared with the respective control groups. Conclusions: The application of Glubran 2 spray on wounds caused by pulmonary resections in pigs proved to have a rapid and effective influence for the purposes of aerostasis without significant differences in air losses and survivals.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
