The dynamics of a lipid bilayer of 1-palmitoyl-2-oleoyl-glycero-3-phospho-ethanolamine, POPE, is investigated under the effect of two electric field intensities. The box of 720 lipids and 13 458 water molecules-plus boundary conditions-undergoes similar re-organizational dynamics in the presence of fields of 0.35 V nm(-1) and 0.5 V nm(-1). Water fingers form followed by some lipid translocation from one layer to the other. The re-organization kinetics is of the second order and is roughly 5 times faster at the higher field. The translocations may occur also upon field switch off, provided that their duration was sufficiently long. Driving few lipid translocations by a macroscopic tool, such as the electric field, appears possible.

Dynamics of a lipid bilayer induced by electric fields / Venturini A.; Zerbetto F.;. - In: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. - ISSN 1463-9076. - STAMPA. - 13:(2011), pp. 9216-9222. [10.1039/c1cp20322c]

Dynamics of a lipid bilayer induced by electric fields

ZERBETTO, FRANCESCO
2011

Abstract

The dynamics of a lipid bilayer of 1-palmitoyl-2-oleoyl-glycero-3-phospho-ethanolamine, POPE, is investigated under the effect of two electric field intensities. The box of 720 lipids and 13 458 water molecules-plus boundary conditions-undergoes similar re-organizational dynamics in the presence of fields of 0.35 V nm(-1) and 0.5 V nm(-1). Water fingers form followed by some lipid translocation from one layer to the other. The re-organization kinetics is of the second order and is roughly 5 times faster at the higher field. The translocations may occur also upon field switch off, provided that their duration was sufficiently long. Driving few lipid translocations by a macroscopic tool, such as the electric field, appears possible.
2011
Dynamics of a lipid bilayer induced by electric fields / Venturini A.; Zerbetto F.;. - In: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. - ISSN 1463-9076. - STAMPA. - 13:(2011), pp. 9216-9222. [10.1039/c1cp20322c]
Venturini A.; Zerbetto F.;
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/121796
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