The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presented
Pileri S.A., Agostinelli C., Bacci F., Sabattini E., Sagramoso C., Falini B., et al. (2011). Pathobiology of ALK-negative anaplastic large cell lymphoma. PEDIATRIC REPORTS, 3(s2), 8-10 [10.4081/pr.2011.s2.e5].
Pathobiology of ALK-negative anaplastic large cell lymphoma.
PILERI, STEFANO;AGOSTINELLI, CLAUDIO;BACCI, FRANCESCO;SABATTINI, ELENA;SAGRAMOSO SACCHETTI, CARLO ALBERTO;PICCALUGA, PIER PAOLO
2011
Abstract
The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presentedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
