Abstract: The decision whether to repair congenital heart defects in patients with raised pulmonary vascular resistance to alleviate pulmonary hypertension is a complex one. The degree of pulmonary vascular disease is of paramount importance. Operating on patients with pulmonary vascular resistance above a certain threshold runs the risk of postoperative persistent pulmonary hypertension and a worse long-term prognosis. This review focuses on patients deemed borderline inoperable or inoperable due to pulmonary vascular disease and asks whether they can be converted to an operable status with pulmonary arterial hypertension-specific drugs that potentially modify the pulmonary vascular lesions and resistan
Can "inoperable" congenital heart defects become operable in patients with pulmonary arterial hypertension? Dream or reality?
GALIE', NAZZARENO;
2012
Abstract
Abstract: The decision whether to repair congenital heart defects in patients with raised pulmonary vascular resistance to alleviate pulmonary hypertension is a complex one. The degree of pulmonary vascular disease is of paramount importance. Operating on patients with pulmonary vascular resistance above a certain threshold runs the risk of postoperative persistent pulmonary hypertension and a worse long-term prognosis. This review focuses on patients deemed borderline inoperable or inoperable due to pulmonary vascular disease and asks whether they can be converted to an operable status with pulmonary arterial hypertension-specific drugs that potentially modify the pulmonary vascular lesions and resistanI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.