Remarkable progress has been made in the treatment of hairy cell leukemia (HCL) in the past 30 years, but often control rather than cure of the disease is obtained. Purine analogues are considered the best treatment, but the optimal strategy is still debated. Allogeneic stem cell transplantation (allo-SCT) is yet an anecdotal therapeutic option for patients who have had multiple relapses of HCL. We describe the case of a young patient with HCL who was treated with several therapeutic approaches without any significant response. Conceivably, this report represents further important evidence of the potential role of allo-SCT in heavily pretreated patients with late-stage HCL.
Zinzani PL, Bonifazi F, Pellegrini C, Casadei B, Argnani L, Motta MR, et al. (2012). Hairy Cell Leukemia: Allogeneic Transplantation Could be an Optimal Option in Selected Patients. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 12, 287-289 [10.1016/j.clml.2012.05.001].
Hairy Cell Leukemia: Allogeneic Transplantation Could be an Optimal Option in Selected Patients.
ZINZANI, PIER LUIGI;BONIFAZI, FRANCESCA;PELLEGRINI, CINZIA;CASADEI, BEATRICE;ARGNANI, LISA;MOTTA, MARIA ROSA;DAN, ELISA;STANZANI, MARTA;ARPINATI, MARIO;BANDINI, GIUSEPPE
2012
Abstract
Remarkable progress has been made in the treatment of hairy cell leukemia (HCL) in the past 30 years, but often control rather than cure of the disease is obtained. Purine analogues are considered the best treatment, but the optimal strategy is still debated. Allogeneic stem cell transplantation (allo-SCT) is yet an anecdotal therapeutic option for patients who have had multiple relapses of HCL. We describe the case of a young patient with HCL who was treated with several therapeutic approaches without any significant response. Conceivably, this report represents further important evidence of the potential role of allo-SCT in heavily pretreated patients with late-stage HCL.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
