Duloxetine is a potent and selective inhibitor of serotonin and norepinephrine reuptake (SNRI) with a weak activity over dopamine reuptake used in the treatment of major depressive disorder. Daily doses of 60 mg are effective in treatment of major depression. There are few cases of isolated duloxetine overdose in humans. We think this is the first report of a generalized tonic-clonic seizure following isolated duloxetine poisoning with a very high dosage.
Generalized tonic-clonic seizure secondary to duloxetine poisoning: a short report with favorable out come / Pellicciari A.; Balzarro B.; Scaramelli A.; Porcelli S.; Serretti A.; De Ronchi D.. - In: NEUROTOXICOLOGY. - ISSN 0161-813X. - STAMPA. - 33:(2012), pp. 189-190. [10.1016/j.neuro.2012.01.009]
Generalized tonic-clonic seizure secondary to duloxetine poisoning: a short report with favorable out come.
SERRETTI, ALESSANDRO;DE RONCHI, DIANA
2012
Abstract
Duloxetine is a potent and selective inhibitor of serotonin and norepinephrine reuptake (SNRI) with a weak activity over dopamine reuptake used in the treatment of major depressive disorder. Daily doses of 60 mg are effective in treatment of major depression. There are few cases of isolated duloxetine overdose in humans. We think this is the first report of a generalized tonic-clonic seizure following isolated duloxetine poisoning with a very high dosage.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
