In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.
No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression / Serretti A.; Chiesa A.; Calati R.; Massat I.; Linotte S.; Kasper S.; Lecrubier Y.; Fink M.; Antonijevic I.; Forray C.; Snyder L.; Bollen J.; Zohar J.; De Ronchi D.; Souery D.; Mendlewicz J.. - In: PSYCHIATRY RESEARCH. - ISSN 0165-1781. - STAMPA. - 188:(2011), pp. 166-169. [10.1016/j.psychres.2010.11.023]
No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression.
SERRETTI, ALESSANDRO;CALATI, RAFFAELLA;DE RONCHI, DIANA;
2011
Abstract
In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
