The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides-PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28-proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.
Donati M., Di Francesco A., Di Paolo M., Fiani N., Benincasa M., Gennaro R., et al. (2011). Activity of cathelicidin peptides against Simkania negevensis. INTERNATIONAL JOURNAL OF PEPTIDES, doi:10.1155/2011/708710, 1-3 [10.1155/2011/708710].
Activity of cathelicidin peptides against Simkania negevensis
DONATI, MANUELA;DI FRANCESCO, ANTONIETTA;FOSCHI, CLAUDIO;CEVENINI, ROBERTO
2011
Abstract
The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides-PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28-proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
