The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides-PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28-proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.
Activity of cathelicidin peptides against Simkania negevensis / Donati M.; Di Francesco A.; Di Paolo M.; Fiani N.; Benincasa M.; Gennaro R.; Cardini P.; Foschi C.; Cevenini R.. - In: INTERNATIONAL JOURNAL OF PEPTIDES. - ISSN 1687-9767. - ELETTRONICO. - doi:10.1155/2011/708710:(2011), pp. 1-3. [10.1155/2011/708710]
Activity of cathelicidin peptides against Simkania negevensis
DONATI, MANUELA;DI FRANCESCO, ANTONIETTA;FOSCHI, CLAUDIO;CEVENINI, ROBERTO
2011
Abstract
The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides-PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28-proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.