The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides-PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28-proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.

Activity of cathelicidin peptides against Simkania negevensis

DONATI, MANUELA;DI FRANCESCO, ANTONIETTA;FOSCHI, CLAUDIO;CEVENINI, ROBERTO
2011

Abstract

The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides-PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28-proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.
INTERNATIONAL JOURNAL OF PEPTIDES
Donati M.; Di Francesco A.; Di Paolo M.; Fiani N.; Benincasa M.; Gennaro R.; Cardini P.; Foschi C.; Cevenini R.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/118168
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