The enantioselective synthesis of pyrazol-3-ones has not been extensively studied in organic synthesis. Here in we report the first asymmetric addition of pyrazolones to maleimides catalyzed by bifunctional thiourea catalysts
A. Mazzanti, T. Calbet, M. Font-Bardia, A. Moyano, R. Rios (2012). Organocatalytic Enantioselective pyrazol-3-one addition to Maleimides. Reactivity and Stereochemical Course. ORGANIC & BIOMOLECULAR CHEMISTRY, 10, 1645-1652 [10.1039/c2ob06553c].
Organocatalytic Enantioselective pyrazol-3-one addition to Maleimides. Reactivity and Stereochemical Course.
MAZZANTI, ANDREA;
2012
Abstract
The enantioselective synthesis of pyrazol-3-ones has not been extensively studied in organic synthesis. Here in we report the first asymmetric addition of pyrazolones to maleimides catalyzed by bifunctional thiourea catalystsFile in questo prodotto:
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